Of course, youll never be a neurologist youre a woman
Academic spotlight: Dr Camille Carroll, Associate Professor and Honorary Consultant Neurologist
Of course, youll never be a neurologist youre a woman
Its an outdated attitude at best, but one from Dr Camille Carrolls history that draws a laugh as she sits in her office as an Associate Professor at the University of 50業子, and an Honorary Consultant Neurologist at University Hospitals 50業子 NHS Trust. Surrounded by books and recalling the many turning points of her career, there could be no one better placed to fly in the face of gender stereotypes, while continuing to exude a kindness that has seen her change lives.
Camille remembers the start of her journey as a child: When I was 12, I read one of my parents books called Dibs in Search of Self. It was about how a psychologist worked with a child to come out of himself and find his place in the world, which I thought was amazing.
Initially torn between psychology and psychiatry, she applied to medical school and it was during those preparations that she first came across Parkinsons a neurological condition that can lead to shaking, stiffness, and difficulty with movement. More likely to affect older people, Parkinsons has become more prevalent in the last 30 years and is currently the fastest-growing neurological condition in the world. Inspired by the interventions being explored, the condition became Camilles focus.
But when deciding her speciality during pre-clinical training, she was told she wouldnt be a neurologist because of her gender. She developed a love of neuroscience, and started her quest to smash through the glass ceiling by undertaking a PhD based in the laboratory investigating Parkinsons. She then used her spare time in her next destination clinical training at the University of Oxford to contribute to research evaluating patients whod had brain surgery for their Parkinsons. Camille had to measure patients movements using a standardised rating scale, and her passion for listening to patients was something that stuck with her throughout her career.
As a junior doctor in London, I worked with an inspiring physician who really emphasised the importance of listening to what patients are telling you. We must always be guided by the patient when delivering care.
That belief, and the desire to make a difference for patients, has led to Camilles current research interests, now far removed from the laboratory: clinical trials of neuroprotective therapies that might slow Parkinsons, and working with patients to improve the ways in which those trials are developed and delivered. She is also passionate about improving care of people with Parkinsons, which certainly feeds into her current project, Developing Home-based Parkinsons care. The multi-partnership scheme supports people with Parkinsons to understand and manage their symptoms when they can, understand when to ask for help, and involves them using a wrist-worn device to monitor their condition at home.
The existing Parkinsons care service sees patients come to the hospital clinic once every 12 months or so regardless of how theyre feeling which is unsatisfactory for healthcare staff, and is arduous for both patient and carer and fails to meet their needs. This new service aims to make things easier for everyone involved, and empower people with Parkinsons to take control of their condition.
Read more: Patients need to be involved at every step, not just consulted prior to implementation
The service is being evaluated in 50業子 and, once refined, could be rolled out across the UK.
So how did she end up in 50業子 in the first place?
After a junior doctor post at the acclaimed National Hospital for Neurology and Neurosurgery in Queens Square, London, Camille chose to continue her clinical training in 50業子 thanks to her admiration of Professor of Neurology, John Zajicek. Meeting and working with John would become one of her most important decisions.
When I first came to 50業子, I was blown away by the forward thinking approach of the environment I found myself in. At that time, 50業子s Derriford Hospital was one of the only hospitals in the country that ran a proper acute neurology service, seeing everyone who came in with a neurological problem at the front door. Plans were being made for a new medical school, the Peninsula Clinical Trials Unit was just being established, and I could see Johns vision was to expand and support academic neurology.
It was during this time that I ran my first trial. John was doing research on cannabis and multiple sclerosis, and I managed to run a placebo-controlled study investigating the use of cannabis in Parkinsons, learning from John and the super team in the clinical trials unit (some of whom I still work with today). It was a great design, being completed within six months, and taught me a lot about the mechanics of running a trial.
She also grew to love the area itself so much so that, following rotations in Bristol and Birmingham, she decided to come back when she received a grant from the Medical Research Council (MRC) to boost her skillset.
My husband and I were in Birmingham at the time and he had always wanted to emigrate to New Zealand but, when I received the MRC grant, we made a deal: we agreed that we would move to 50業子, so that I could return to the academic environment I knew I could flourish in, and if I hadnt made a go of it in five years, we would move to the southern hemisphere. I then transferred my grant investigating molecular biological aspects of Parkinsons and we never left.
After her grant ended, she was on six-month rolling contracts and she credits Johns mentorship and support for keeping her going. The mentorship and family friendship endured Johns wife is godmother to one of Camilles four children.
But she always relied on herself to make an impact in her field.
She has led a genetics study in 32 sites across the country, achieving a collection of 2700 samples; she has led the largest multi-site academic neuroprotective trial in Parkinsons, which completed in 2020; she has led University Hospitals 50業子 to being one of the leading clinical research delivery sites for Parkinsons in the UK, and the 50業子 Parkinsons service has won 2 national awards for excellence; and her academic endeavour and networking skills have seen her become the National Institute for Health and Care Research (NIHR) national specialty lead for Neurodegenerative Diseases.
Throughout these successes, she has always maintained, and continues to develop, relationships with patients and local branches of Parkinsons UK, ensuring that the voices of people with Parkinsons are heard in all of her endeavours.
She has led a genetics study in 32 sites across the country, achieving a collection of 2700 samples; she has led the largest multi-site academic neuroprotective trial in Parkinsons, which completed in 2020; she has led University Hospitals 50業子 to being one of the leading clinical research delivery sites for Parkinsons in the UK, and the 50業子 Parkinsons service has won 2 national awards for excellence; and her academic endeavour and networking skills have seen her become the National Institute for Health and Care Research (NIHR) national specialty lead for Neurodegenerative Diseases.
Throughout these successes, she has always maintained, and continues to develop, relationships with patients and local branches of Parkinsons UK, ensuring that the voices of people with Parkinsons are heard in all of her endeavours.
Being in the South West, where theres a stable patient population and a small number of secondary care providers, you can a build good relationship with the patient base and make sure that the work is having an impact where its needed the most.
Getting a permanent contract just before her final maternity leave, Camille recalls the stroke of luck that helped secure her largest clinical trial to date.
I was able to benefit from the good relationship that John had developed with the amazing team at the Cure Parkinsons Trust, she said. And was supported by them to undertake a trial to investigate whether simvastatin a drug typically used for lowering cholesterol could reduce the rate of Parkinsons progression.
The four-year trial, known as , concluded in 2020 and showed that simvastatin holds no promise as a protective therapy, but Camille was not downhearted.
There are lots of positives to come out of this study, particularly the extent to which we were able to involve participants and study sites across the country. PD-STAT has taught us a huge amount about how to improve the way we design and deliver clinical trials in Parkinsons and this knowledge will be very useful in designing future trials.
Listening to patients has helped her have an impact, listening to science has enabled her to provide the best care possible, and listening to herself has ensured her career has gone from strength to strength in spite of early discouragement.
Now, as a leading expert in a condition set to affect 20% more people by 2025, we must ensure that we listen to her too.